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南京科佰生物科技有限公司
主营产品: atcc代理,ATCC细胞系,ATCC细胞株,ATCC细胞库购买 |
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更新时间:2024-02-01 09:17:27浏览次数:466
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CBP10341 | |
Format | Genomic DNA |
Description | EGFR C797S lies within the ATP-binding pocket in the protein kinase domain of the Egfr protein (PMID: 25964297). C797S has been demonstrated to confer resistance to third-generation EGFR inhibitors (PMID: 25964297, PMID: 25948633, PMID: 29410323), but has not been biochemically characterized and therefore, its effect on Egfr protein function is unknown (PubMed, Jun 2018). |
Technical Data | |
DNA Change: | c.2389T>A |
AA Change | p.C797S |
Mutation type | Substitution - Missense |
Zygosity | Heterozygous |
Allelic Frequency | 50% |
Transcript | ENST00000275493 |
Chr position(GRCh37) | COSM6493937 |
Chr position(GRCh37) | chr7:55249091 |
Buffer: | Tris-EDTA |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1µg |
Concentration | Download for COA |
Purofication | Download for COA |
DNA electrophoresis | Download for COA |
Sanger sequencing | |
Storage | 4℃ |
Expiry | 36 months from the date of manufacture |