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南京科佰生物科技有限公司
主营产品： atcc代理,ATCC细胞系,ATCC细胞株,ATCC细胞库购买 |
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南京科佰生物科技有限公司
主营产品： atcc代理,ATCC细胞系,ATCC细胞株,ATCC细胞库购买 |
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| 参考价 | 面议 |
更新时间：2023-04-11 15:37:02浏览次数：290
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CBP10538 | |
| Format | Genomic DNA |
| Description | NPM1, nucleophosmin, is a phosphoprotein that shuttles between the nucleus and cytoplasm, and is involved in several cellular processes including ribosomal processing and export, chromatin remodeling, DNA replication and repair, and cell cycle control (PMID: 29157973, PMID: 23436734). NPM1 is frequently mutated in acute myeloid leukemia (PMID: 29157973, PMID: 23436734, PMID: 30122998, PMID: 29785446, PMID: 32203582, PMID: 32609823) and overexpression is implicated with poor prognosis in hematological and solid tumors (PMID: 32071709). |
| Technical Data | |
| DNA Change | c.829C>T |
| AA Change | p.R277W |
| Mutation type | Missense_Mutation |
| Zygosity | Heterozygous |
| Allelic Frequency | 3.58% |
| Transcript | NM_002520.7 |
| Cosmic ID | COSM3339473 |
| Chr position(GRCh37) | chr5:170834761 |
| Buffer | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing | Download for COA |
| Storage | 4℃ |
| Expiry | 36 months from the date of manufacture |
