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南京科佰生物科技有限公司
主营产品： atcc代理,ATCC细胞系,ATCC细胞株,ATCC细胞库购买 |
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南京科佰生物科技有限公司
主营产品： atcc代理,ATCC细胞系,ATCC细胞株,ATCC细胞库购买 |
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更新时间：2022-09-02 10:39:47浏览次数：462
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| 供货周期 | 现货 | 规格 | T-25 Flask |
|---|---|---|---|
| 货号 | CBP90006 | 应用领域 | 生物产业 |
| 主要用途 | 仅限科研使用 |
| Panel-Ref® EGFR Cocktail II 5% Reference Standard | ||||||
| Cat No. | CBP90006 | |||||
| Format | Genomic DNA | |||||
| Description | 包含EGFR常见突变的5个突变，适用于评估EGFR相关的检测，作为质控品、参考品等。 | |||||
| Gene | AA Change | CDS Change | Exon | Cosmic ID | AF% | Chr position (GRCh37) |
| EGFR | p.E746_A750delELREA | c.2236_2250del15 GAATTAAGAGAAGCA>- | 19 | COSM6225 | 5% | chr7:55242466_55242480 |
| EGFR | p.G719A | c.2156G>A | 18 | COSM6239 | 5% | chr7:55241708 |
| EGFR | p.V769_D770insASV | c.2307_2308ins GCCAGCGTG | 20 | COSM12376 | 5% | chr7:55249010_55249011 |
| EGFR | p.C797S | c.2389T>A | 20 | COSM6493937 | 5% | chr7:55249091 |
| EGFR | p.L861Q | c.2582T>A | 21 | COSM6213 | 5% | chr7:55259524 |
| Product Information | ||||||
| Intended Use | Research Use Only | |||||
| Unit Size | 1ug/vial * 1 vial | |||||
| Concentration | Download for COA | |||||
| Purity | Download for COA | |||||
| DNA electrophoresis | Download for COA | |||||
| Storage | 4°C | |||||
| Expiry | 36 months from the date of manufacture | |||||
| 如下表是EGFR常见的突变位点，我们可以按照您的需求定制EGFR Panel，或者定制其中没有的位点 | ||||||
| Gene | AA Change | CDS Change | Exon | Cosmic ID | AF% | Chr position (GRCh37) |
| EGFR | p.C797S | c.2389T>A | 20 | COSM6493937 | 50% | chr7:55249091 |
| EGFR | p.C797S | c.2390G>C | 20 | COSM5945664 | Coming soon | chr7:55249092 |
| EGFR | p.T790M | c.2369C>T | 20 | COSM6240 | 50% | chr7:55249071 |
| EGFR | p.L861Q | c.2582T>A | 21 | COSM6213 | 100% | chr7:55259524 |
| EGFR | p.V769_D770insASV | c.2307_2308ins GCCAGCGTG | 19 | COSM12376 | 100% | chr7:55249010_55249011 |
| EGFR | p.E746_A750delELREA | c.2235_2249del15 GGAATTAAGAGAAGC>- | 19 | COSM6223 | 100% | chr7:55242465_55242479 |
| EGFR | p.E746_A750delELREA | c.2236_2250del15 GAATTAAGAGAAGCA>- | 19 | COSM6225 | 50% | chr7:55242466_55242480 |
| EGFR | p.L747_A750>P | c.2239_2248TTAAGAGAAG>C | 19 | COSM12382 | 100% | chr7:55242469_55242478 |
| EGFR | p.G719A | c.2156G>C | 18 | COSM6239 | 100% | chr7:55241708 |
| EGFR | p.G719S | c.2155G>A | 18 | COSM6252 | 33.33% | chr7:55241707 |
| EGFR | p.G719C | c.2155G>T | 18 | COSM6253 | Coming soon | chr7:55241707 |
| EGFR | p.S768I | c.2303G>T | 20 | COSM6241 | 100% | chr7:55249005 |
| EGFR | p.A763_Y764insFQEA | c.2290_2291ins tccaggaagcct | 19 | COSM26720 | 100% | chr7:55248992_55248993 |
| EGFR | p.H773 V774insNPH | c.2319_2320ins AACCCCCAC | 20 | COSM12381 | 100% | chr7:55249021_55249022 |
| EGFR | p.D770_N771insSVD | c.2311_2312ins GCGTGGACA | 20 | COSM13428 | 100% | chr7:55249013..55249014 |
| EGFR | p.L858R | c.2573T>G | 21 | COSM6224 | 50% | chr7:55259515 |
| EGFR | p.L747_P753>S | c.2240_2257del18 TAAGAGAAGCAACATCTC | 19 | COSM12370 | 100% | chr7:55242470_55242487 |
